Kolexia
Verhaeghe Pierre
Pharmacien
Hôpital Nord Grenoble
La Tronche, France
57 Activités
0 Followers

Scientifique
Digital
Production scientifique
Activités par an
Expertise
Sujets de recherche
{{person.topmesh1.name}} Paludisme Leishmaniose Tumeurs du sein Oedème Urémie Grippe humaine Tuberculose Insuffisance rénale chronique Paludisme à Plasmodium falciparum

Industries

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Dernières activités

Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound.
Bioorganic & medicinal chemistry   28 février 2024
Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability.
European journal of medicinal chemistry   13 octobre 2023
New antiplasmodial 4-amino-thieno3,2-dpyrimidines with improved intestinal permeability and microsomal stability.
European journal of medicinal chemistry   13 janvier 2023
Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo1,2- pyridine Antileishmanial Pharmacophore.
Pharmaceuticals (Basel, Switzerland)   13 août 2022
Drug screening approach against mycobacterial fatty acyl-AMP ligase FAAL32 renews the interest of the salicylanilide pharmacophore in the fight against tuberculosis.
Bioorganic & medicinal chemistry   29 juillet 2022
Synthesis of antiplasmodial 2-aminothieno3,2-dpyrimidin-4(3H)-one analogues using the scaffold hopping strategy.
European journal of medicinal chemistry   20 juillet 2022
Pd-catalyzed C-C and C-N cross-coupling reactions in 2-aminothieno3,2- pyrimidin-4(3 )-one series for antiplasmodial pharmacomodulation.
RSC advances   08 juillet 2022
4-Substituted Thieno3,2- pyrimidines as Dual-Stage Antiplasmodial Derivatives.
Pharmaceuticals (Basel, Switzerland)   01 juillet 2022
A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites.
Microbiology spectrum   29 septembre 2021
Antiplasmodial 2-thiophenoxy-3-trichloromethyl quinoxalines target the apicoplast of Plasmodium falciparum.
European journal of medicinal chemistry   29 juillet 2021